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Combo-pilling may be the newest fad or even better the newest ahead under scrutiny and thus it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that since right now there are no long term prescription slimming capsules that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug may also raise blood pressure level and heartrate, and really should not be used in people who have a history of cardiac event or stroke in the earlier six months. 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